Solid Form Solutions has invested in Blazemetrics next generation 3-in-1 in process analytical technology (PAT). The Blaze 3-in-1 system combines, high resolution microscopy, particle sizing and particle-focused Raman into one compact probe.  The real time in-situ process analytical tool can be used from 5mL scale for pre-clinical/early phase compounds through to scale-up and tech transfer. The Blaze 3-in-1 has the capability to simultaneously characterize particle shape, size, crystallinity, and polymorph form, in real-time, in the same region inside a chemical reactor.

Stephen Watt, president of SFS says, “Unlike the multiple, and separate, probes that have been used in the past to characterise particles, the Blazemetric 3-in-1 PAT tools exemplify the next generation of this technology. By incorporating the Blaze 3-in-1 into SFS work programs, SFS demonstrates that it is taking the next step in solid form science and scale-up crystallization. Our audacious mindset to evolve this area of science continues to drive new and better screening and scale-up methodologies.”

By making this investment, the Blaze 3-in-1 gives an unprecedented level of insight into particle and process behavior often reducing the number of experiments required while at the same time the single probe reduces setup time and impact on mixing and other variables.


Immersion probe










3840 x 2160 computer monitor resolution is required to see the full image resolution of Blaze Microscopy. This resolution is not typically supported on standard desktop computers.