Pharmaceutical salt screening and development

Solid Form Solutions aim to deliver a salt screening and selection program that is based on crystal engineering principles, delivering developable salt forms that satisfy wider development requirements.

Our services are focused on screening a range of counterions based on:

  • The pKa of the API
  • The market precedence of each counterion
  • The available toxicology data of each counterion
  • Crystal engineering assessments
  • Past salt screening experience

We aim to deliver a number of pharmaceutically acceptable salts (sometimes called versions) that satisfy specific physical and developabilty criteria.

Our risk based approach ensures that all our salt studies are carried out within ICH guidelines and alerts our clients to any potential problems that might occur in downstream development.

Similar to our polymorph screening program, the scope of our salt selection studies can be tailored to meet the requirements of our customers.