Pharmaceutical API development and scale up...
Solid Form Solutions Ltd are pleased to unveil their Custom Synthesis Service to complement their solid form screening programs. Using a Quality By Design approach, the integration of the two services provides a powerful and rapid low-risk route to manufacture.
Our experienced synthetic chemistry team are capable of locating the first route to a drug molecule and delivering a scaled-up, optimised, process. Our capabilities include:
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Laboratory synthesis of novel compounds and intermediates
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Expansion of Molecular Libraries
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Hit to Lead Optimisation
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Lead Compound Scale-up for Advanced studies
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Extensive analytical support and services
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Synthesis from the milligram scale to pilot plant
Our specialized equipment capability includes:
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Impurity isolation and identification
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Autoclaves for hydrogenation and pressure reaction
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Fractional Distillation
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Pilot plant reactors (including continuous flow)
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High-Field NMR ¹H, ¹³C, N and ³¹P nuclei (including 2D NMR for full structure elucidation)
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Mass spectrometry (EI, CI, ESI and MALDI)
Whether our synthetic work programs are used separately, or in tandem with a screening activity, SFS will deliver the most efficient synthetic chemistry.
Would you like to know more?
If you have any questions regarding this are of our service range please contact us.
